You can purchase static straps that increase the conductivity between yourself and the floor, which should prevent most static buildup, unless your floor has a very high resistance as well.
It will probably be easier, however, to change the clothing you wear. Synthetic fibers are plastic, and not only build static charge over time, but prevent it from normalizing. Natural fibers such as cotton and wool will build up significantly less charge than synthetic fibers. If you wear layers, and your work chair is synthetic, the problem will be compounded. Try wearing a cotton t-shirt and cotton jeans, for instance, and you should immediately notice a reduction in static buildup. Couple a 50/50 cotton/poly shirt with a polyester fleece pullover, rubbing against a synthetic cloth covered chair, though, and you will be raising little lightning bolts constantly at your workstation and as you move around.
You can also buy static discharge products that will safely discharge you while you work. Aside from the foot strap above, which depends on a conductive floor, you can use a static discharge mat under your keyboard on your desk which you can touch with your wrists to dissipate any static charge you might be holding prior to typing.